mRNA-seqを用いたAngelica acutilobaの遺伝子発現解析

江口 遼平 (1451019)


Angelica acutiloba is a perennial herb from the family Apiaceae or Umbelliferous. Its root was used in Kampo medicine, which is a Japanese adaptation of Traditional Chinese medicine. Angelica acutiloba has the defense mechanism to insect damage, and makes BETA-CARYOPHYLLENE which has the property of inviting a bee to exterminate noxious insects. In addition, BETA-CARYOPHYLLENE is a medically effective ingredient. In a word, medically effective ingredients in Angelica acutiloba increase by insect damage. The purpose of this study is unraveling the defense mechanism of it.

In this study, Angelica acutiloba is analyzed by differential expression analysis of RNA-seq data in order to elucidate the defense mechanism of it. We detected new candidate genes potentially and metabolic pathway related to damage by vermin.