コロキアムB発表

日時: 06月17日 (Tue) 3限目(13:30-15:00)


会場: L2

司会: Isidro Butaslac
DANG VAN TRONG D, 中間発表 ヒューマンロボティクス 和田 隆広, 松原 崇充, 織田 泰彰, 劉 海龍, 本司 澄空

Title:  A Cooperation Control Framework Based on Admittance Control and Time-varying Semi-passive Velocity Field Control for Human-Robot Co-carrying Tasks 

Abstract: Developing a cooperation control framework for human-robot co-carrying tasks in achieving safe interaction and completing the shared tasks, especially in scenarios where human intentions vary due to changes in the environment or task demands, remains an open challenge. Passivity-based control theory realizes safe operation by preserving the energetically passive relationship between the closed-loop system and its physical environment. However, solely adhering to passivity constraints may impose fundamental limitations on control performance and, in some cases, prevent the successful execution of controlled tasks. To address these issues, a cooperation control framework for human-robot co-carrying tasks was constructed by utilizing a reference generator and a time-varying semi-passive velocity field control in this study. Firstly, the human motion predictions are corrected in the event of prediction errors based on human-robot conflicts measured by the interaction forces through admittance control, thereby mitigating conflict levels. Subsequently, a time-varying semi-passive velocity field control approach is proposed, which utilizes the output of the motion generator to regulate robot behaviors during physical interaction with the human. In this manner, the proposed framework relaxes the inherently conservative nature in a controlled manner, which ensures the passivity of the closed-loop system when the energy level exceeds the designed one; and vice versa. Furthermore, the proposed control approach ensures that the system's kinetic energy is compensated within a finite time interval. The passivity, stability, convergence rate of energy, and power flow regulation are analyzed from theoretical viewpoints. 

Language of the presentation: English

 
LIU HUAKUN D, 中間発表 サイバネティクス・リアリティ工学 清川 清, 和田 隆広, 内山 英昭, Perusquia Hernandez Monica, 平尾 悠太朗
 

日時: 06月17日 (Tue) 3限目(13:30-15:00)


会場: L3

司会: 松井 智一
HOVHANNISYAN ANI D, 中間発表 ソフトウェア工学 松本 健一, 飯田 元, Raula Gaikovina Kula, 嶋利 一真, Fan Youmei
 
MUHAMMAD ALQAAF SUBANDOKO D, 中間発表 計算システムズ生物学 金谷 重彦, 松本 健一, MD.Altaf-Ul-Amin, 小野 直亮

Title

Integrative Computational Pipeline for Natural Product-Based Inhibitors of Viral Diseases

Abstract

Building on our published work against SARS-CoV-2, where we clustered 204 spike-glycoprotein sequences, matched 33,722 binding molecules to 52,107 secondary metabolites (SMs) from KNApSAcK, and identified fourteen promising natural inhibitors, we are now extending the same integrative pipeline to HIV-1. For the HIV-1 study, we first assembled an Ayurvedic NP library of ~3,200 unique SMs by mining KNApSAcK and hand-curated literature sources. We gathered FASTA sequences for all HIV-1 protein targets (protease, reverse transcriptase, integrase, envelope glycoprotein) from known protein targets of each SM in our Ayurvedic library. We then computed k-mer (k=3) frequency vectors for each FASTA, calculated pairwise similarity scores, and performed clustering using DPClusSBO to group proteins with similar sequence features. By mapping each SM to its cluster of protein targets, we can prioritize those SMs whose native targets cluster most closely with one or more HIV-1 proteins, thereby harnessing sequence-based "target homology" as a filter. Representative SMs from these clusters have now been selected for the upcoming docking stage against HIV-1 protease, RT, integrase, and Env. The resulting subset will proceed to in silico docking, Lipinski and bioavailability filtering for validation.

Language

English