ゼミナール発表

日時: 7月22日(金)3限 (13:30-15:00)


会場: L2

司会:松原 崇充
Dy, Mary-Clare Clarin M2回目 湊 小太郎 杉本 謙二 杉浦 忠男
Integration of Axial Displacement in Optical Tweezers
Optical tweezers is an optical manipulation technique where tiny particles can be trapped and manipulated using a highly focused laser beam. Since the 1980s, it has become an integral part of studying the mechanics of biomolecules and biomolecular processes, specifically because, aside from being able to move particles in the nanometer scale, it also has the capability to measure pico- and nano-Newton forces of objects. Recent researches now consider three-dimensional manipulation and force measurement. However, these researches utilize expensive and complicated devices in order to change the focus of the laser beam in the axial direction. In my research, our aim is to integrate the axial displacement in our existing Optical Tweezers setup just by moving one lens (L1). Preliminary experiments show that our technique is able to move the microbead in the axial direction: Using a bead with diameter of 4.26 , we moved the L1 for 600 mm and the corresponding range of axial displacement of the bead was 4 オm. For a 2.1 オm bead, moving the L1 for 120 mm corresponds to a change in distance of 2 オm. The next task of the research is tos test the technique with cells. For the future work, we plan to incorporate the axial displacement technique in the Cell Palpation System.